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Faculty And Section Heads > Dr. Jackie Smith   |  Login

Jacqueline L. Smith, BS, MS, PhD

Phone: 859-257-7559
Fax: 859-255-1624
E-mail: jsmit8@uky.edu

Epidemiology Section Head

Founder, Animal Disease & Diagnosis Mapping Initiative

PhD - University of Kentucky
MSc - University of Wisconsin-Madison
BSc - Berea College, Kentucky
Diplomate, American Veterinary Epidemiology Society
Member of the American College of Epidemiology

Selected recent publications/communications:

Carter CN, Smith JL. A proposal to leverage high-quality veterinary diagnostic laboratory large data streams for animal health, public health, and One Health. Journal of Veterinary Diagnostic Investigation. 2021;33(3):399-409. doi:10.1177/10406387211003088

Infectious or Contagious – Which is it?  Jackie Smith and Emma Adam.  Equine Science Review, Issue 13, April 21, 2021.

Odoi A, Samuels R, Carter CN, Smith J (2021) Antibiotic prescription practices and opinions regarding antimicrobial resistance among veterinarians in Kentucky, USA. PLoS ONE 16(4): e0249653.

Vaccines – Where Would we be Without Them?  Emma Adam and Jackie Smith.  Equine Science Review, Issue 12, March 22, 2021.  https://equine.ca.uky.edu/content/science-sleuths-science-shapes-diagnostic-tests%E2%80%A6vaccines-where-would-we-be-without-them

Zoonotic?  It Might Not Mean What You Think it Means.
  Jackie Smith and Emma Adam.  Equine Science Review, Issue 11, February 20, 2021. https://equine.ca.uky.edu/content/science-sleuths-science-shapes-diagnostic-tests-zoonotic-it-might-not-mean-what-you-think-it

Nocardioform placentitis: A continuing question. 
Hossam E. Ali, Barry A. Ball, Carleigh Fedorka, Kirsten E. Scoggin, Maria Schnobrich, Eral Erol, Rebecca E. Ruby, Jacqueline L. Smith, Craig N. Carter, Pouya Dini.  AAEP, 2021.

Endemic, Epidemic or Pandemic?  Jackie Smith
and Emma Adam.  Equine Science Review, Issue 9, December 18, 2020.  https://equine.ca.uky.edu/content/science-sleuths-science-shapes-diagnostic-tests-endemic-epidemic-or-pandemic.

PCR, qPCR –What’s the difference? 
Emma Adam and Jackie Smith.  Equine Science Review, Issue 8, November 20, 2020.  https://equine.ca.uky.edu/content/science-sleuths-science-shapes-diagnostic-tests-pcr-qpcr-%E2%80%93-what%E2%80%99s-difference.

What Does R0 Mean?  Jackie Smith
and Emma Adam.  Equine Science Review, Issue 7, October 19, 2020.  https://equine.ca.uky.edu/content/science-sleuths-science-shapes-diagnostic-tests-what-does-ro-mean.

Wanted Dead or Alive- Does PCR supersede traditional techniques? 
Emma Adam and Jackie Smith.  Equine Science Review, Issue 6, September 15, 2020.  https://equine.ca.uky.edu/content/september-2020-equine-science-review.

What does ‘Statistically Significant’ actually mean?  Jackie Smith
and Emma Adam.  Equine Science Review, Issue 5, August 17, 2020.  https://equine.ca.uky.edu/content/august-2020-equine-science-review.

PCR: what’s behind this commonly used acronym? 
Emma Adam and Jackie Smith.  Equine Science Review, Issue 4, July 15, 2020.  https://equine.ca.uky.edu/content/july-2020-equine-science-review.

Antimicrobial susceptibility patterns of Rhodococcus equi from necropsied foals with rhodococcosis.  Erdal Erol, Stephen Locke, Ahmad Saied, Rebecca Ruby, Michael Cruz-Penn, Jacqueline Smith, Jordan Fortner, Craig Carter.  Veterinary Microbiology.  Vet Microbiol. 2020 Mar;242:108568. doi: 10.1016/j.vetmic.2019.108568. Epub 2020 Jan 7. PMID: 32122582.

Leptospirosis: An important infectious disease in North American horses.  T.J. Divers, Y.F. Chang, N.L. Irby, J.L. Smith, C.N. Carter.  Equine Veterinary Journal.  January, 2019.  https://doi.org/10.1111/evj.13069

Emergence of resistance to macrolides and rifampicin in clinical isolates of Rhodococcus equi from foals in central Kentucky, USA: 1995:2017.  Laura Huber, Steeve Giguère, Nathan M. Slovis, Craig N. Carter, Bonnie S. Barr, Noah D. Cohen, Justine Elam, Erdal Erol, Stephan J. Locke, Erica D. Phillips, Jacqueline L. Smith.  Journal of Antimicrobial Chemotherapy, 2018 Dec 21;63(1). pii: e01714-18. doi: 10.1128/AAC.01714-18. Print 2019 Jan.

Temporal trends and predictors of antimicrobial resistance among Staphylococcus spp. isolated from canine samples submitted to a diagnostic laboratory. Julia G. Conner; Jackie Smith; Stephen Locke; Erica Phillips; Craig N. Carter; Erdal Erol; Agricola Odoi.  PLoS One.  PONE-D-17-40627R2

An epidemiologic study of antimicrobial resistance of Staphylococcus spp. Isolated from equine samples submitted to a diagnostic laboratory.  Ronita Adams, Jackie Smith, Stephen Locke, Erica Phillips, Craig Carter, Erdal Erol, Agricola Odoi.  2018.  BMC Veterinary Research.  14:42.  https://doi.org/10.1186/s12917-018-1367-6

Nocardioform placentitis from an epidemiological view. Dr. Jackie Smith.  Equine Disease Quarterly, April 2017: Vol 26 Number 2.  http://gluck.ca.uky.edu/equine-disease-quarterly

Syndromic Surveillance and Spatial Epidemiology.  Dr. Jacqueline Smith. Equine Disease Quarterly, April 2016: Vol 25 Number 2.  www2.ca.uky.edu/gluck/q_apr16.asp

Elevated Serum Amyloid A levels in cases of aborted equine fetuses due to fetal and placental infections.  Erdal Erol, David Horohov, Carney Jackson, Stephen Locke, Jaqueline Smith, Craig Carter.  Theriogenology.  2016. September;86(4):971-975.

Equine Tyzzer's Disease Update: January 1993- April 2015.  Dr. Jacqueline Smith. Equine Disease Quarterly, July 2015: Vol 24 Number 3.

Discrimination of healthy versus sick steers by means of continuous remote monitoring of animal activity.  Jacqueline L. Smith, Eric S. Vanzant, Craig N. Carter, Carney B. Jackson.  Am J Vet Res.  2015.  August;76(8):739-744.        

Increased incidence of Corynebacterium Psuedotuberculosis infection in equids across the United States from 2003-2012.  Isabelle Kilcoyne, MVB; Sharon J. Spier, DVM, PhD, ACVIM; Craig N. Carter, DVM, PhD, ACVPM; Jacqueline Smith, PhD; Amy Swinford, DVM and Noah D. Cohen, VMD, MPH, PhD, ACVIM.  JAVMA 2014;245:309-314.

A diagnostic evaluation of real-time PCR, fluorescent antibody, and microscopic agglutination tests in cases of equine abortion. E.Erol, C.B. Jackson, M. Steinman, J. Donahoe, N. Kelly, S. Locke, J.L. Smith, C.N. Carter .  Equine Veterinary Journal, April 2014. 

Equine Monocytic Ehrlichiosis: Kentucky Case Series: January 2008 – August 2013.  Craig Carter, Jacqueline Smith, Erdal Erol.  Equine Disease Quarterly, October 2013, Vol 22 Number 4.

Carter CN, Cassady J, Ronald N, Gaskill C, Arnold M, Smith J, Northington, W: Knowledge-based differential diagnostic and accessioning mobile application to improve ruminant laboratory case submissions.  Proceed of the XVI International Symposium of the WAVLD, Jun, 2013, Berlin, Germany pp 58-59.

Association of airborne concentrations of virulent Rhodococcus equi with location (foaling stall versus paddock) and month (January through June) at 30 horse breeding farms in central Kentucky.  Noah D. Cohen, VMD, MPH, PhD; Kyle R. Kuskie, BS; Jacqueline L. Smith, BS, MS; Nathan M. Slovis, DVM; Stuart E. Brown II, DVM; Randolph S. Stepusin, BS; M. Keith Chaffin, DVM, MS; Shinji Takai, DVM, PhD; Craig N. Carter, DVM, PhD.  Am J Vet Res. 2012.  Oct; 73(10):1603-1609.

Associations between the Exposure to Airborne Virulent Rhodococcus equi and the Incidence of R equi pneumonia among Individual Foals.Kyle R. Kuskie,  Jacqueline L. Smith, Samiran Sinha, Craig N. Carter, M. Keith Chaffin, Nathan M. Slovis, Stuart E. Brown II, Randolph S. Stepusin, Shinji Takai,  Noah D. Cohen.  Journal of Equine Veterinary Science 31: 463-469.  2011.

Effects of farm location and time of day on airborne concentrations of virulent Rhodococcus equi at horse breeding farms. Kyle R. Kuskie, Jacqueline L. Smith, Naisyin Wang, Craig N. Carter,  M. Keith Chaffin, Randolph S. Stepusin, Anthony E. Cattoi, Shinji Takai, Noah D. Cohen.  Am J Vet Res. 2011.  Jan; 72(1):73-9.


Frequency of Rhodococcus equi in feces of mares in central Kentucky.

Stephanie Buntain, Craig Carter, Kyle Kuskie, Jacqueline Smith, Randolph Stepusin,  M. Keith Chaffin, Shinji Takai, Noah Cohen.   Journal of Equine Veterinary Science, Vol. 30, No. 4, April, 2010. 


Agricola Odoi; Craig Carter; Jeremy Riley; Jackie Smith; Roberta Dwyer. Application of Automated Surveillance Data Analysis System (ASDAS) in a laboratory-based early warning system for detection of an abortion outbreak in mares.  Am J Vet Res, Vol. 70, No. 2, February, 2009.

Cohen ND, Carter CN, Scott HM, Chaffin MK, Smith JL, Grimm MB, Kuskie KR, Takai S, Martens RJ:  Association of soil concentrations of Rhodococcus equi foal pneumonia at farms in Central Kentucky.  Am J Vet Res, Vol 69, No. 3, March, 2008.

Hardin, Brian; Campbell, Kenneth; Smith, Jeffrey; Arbogast, Sandrine; Smith, Jacqueline; Moylan, Jennifer; Reid, Michael. TNFα Acts Via TNFR1 and Muscle-Derived Oxidants to Depress Myofibrillar Force in Murine Skeletal Muscle.  J Appl Physiol, Mar 2008; 104: 694 – 699.

Carter CN, Odoi A, Riley J, Smith J, Stepusin R, Cattoi T, McCollum S: Laboratory-based early animal disease detection utilizing a prospective space-time permutation scan statistic.  Proceed of the XIII International Symposium of the WAVLD, 2007, p96.

Carter CN, Donahue M, Smith J, Steinman M, Donahoe J:  Characteristics of an outbreak of equine leptospiral abortion in the Bluegrass region of Kentucky.  Proceed 50th Conf. AAVLD, p 83, Oct, 2007.

Carter CN, Odoi A, Riley J, Smith J, Stepusin R, Cattoi T, McCollum Stu:  Laboratory-based early animal disease detection utilizing a prospective space-time permutation scan statistic.  Proceed 50th Conf. AAVLD, p 69, Oct, 2007.

Carter CN, Donahue M,  Donahoe J, Smith J:  Equine leptospirosis outbreak.  Kentucky Veterinary News, Spring, 2007.

Arbogast, S; Smith, J; Matuszczak, Y; Hardin, B; Moylan, J; Smith, J; Ware, J; Kennedy, A; Reid, M.B.  Bowman-Birk Inhibitor Concentrate Prevents Atrophy, Weakness, and Oxidative Stress in Soleus Muscle of Hindlimb-Unloaded Mice. J Appl Physiol, Mar 2007; 102: 956 - 964.

Arbogast S., J.L. Smith, A.R. Kennedy, and M.B. Reid. Dietary interventions reduce muscle weakness in unloaded muscle. FASEB J. 19 : A 568, 2005.

Hardin B.J., Smith J.L., Arbogast S., and M.B. Reid.  Muscle weakness caused by Tumor Necrosis Factor-alpha (TNFa).  Physiologist. 47:290, 2004.

Smith J.L. and L.G. Sheffield.  Local expression of leptin receptor is required for mammary alveolar development.  FASEB J.  18:A451.1.  2004.

Smith JL and L.G. Sheffield. Production and regulation of leptin in bovine mammary epithelial cells. Domest Anim. Endocrinol. 2002 May; 22(3):145-54.

Smith J.L. and L.G. Sheffield.  Expression of leptin and leptin receptor messenger RNA during mammary gland development in mice.  J. Anim. Sci. Vol. 81, Suppl.1/ J. Dairy Sci. Vol. 86, Suppl. 1.  2002.

Smith J.L. and L.G. Sheffield.  Impact of growth factors on expression of leptin and leptin receptor in cultured mammary epithelial cells.  J. Anim. Sci. Vol. 81, Suppl.1/ J. Dairy Sci. Vol. 86, Suppl. 1.  2002.

Smith J.L. and L.G. Sheffield.  Local ablation of leptin receptor inhibits mammary alveolar development.  J. Anim. Sci. Vol. 81, Suppl.1/ J. Dairy Sci. Vol. 86, Suppl. 1.  2002.

Smuga-Otto K.M.S., W. Luo, J.L. Smith, E. Reinfried, and L.G. Sheffield.  Production of DNA arrays by expression profiling.  J. Anim. Sci. Vol. 81, Suppl.1/ J. Dairy Sci. Vol. 86, Suppl. 1.  2002.

PubMed Sequence Submissions

Sheffield,L.G., Smith,J.L. and Smuga-Otto,K.M.S.  Bos taurus leptin mRNA, partial cds.  PubMed accession number:  AY044438.  May, 2003.